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  • ISBN-10 ‏ : ‎ 1464126143
  • ISBN-13 ‏ : ‎ 978-1464126147
  • Author:  Cox Doudna O’Donnell

Learn how science is done as Molecular Biology walks you through the fundamental concepts of science today.

 

Table of Content:

Chapter 4

 

  1. Which of the following amino acids has an aromatic R group?

 

  1. aspartate
  2. proline
  3. threonine
  4. tyrosine
  5. arginine

 

Answer: D

Section: 4.1

Level: Easy

Blooms: Remembering

 

 

  1. Which of the following amino acids has a nonpolar thioether R group?

 

  1. cysteine
  2. serine
  3. tryptophan
  4. methionine
  5. None of the choices given is correct.

 

Answer: D

Section: 4.1

Level: Medium

Blooms: Remembering

 

 

  1. Which of the following amino acids is/are negatively charged at physiological pH?

 

  1. serine
  2. aspartate
  3. glutamate
  4. serine, aspartate, and glutamate
  5. aspartate and glutamate

 

Answer: E

Section: 4.1

Level: Medium

Blooms: Understanding

  1. Considering normal human blood ranges from pH 7.35 to pH 7.45, Table 4.1 predicts that:

Molecular Biology Principles and Practice

  1. the R group of aspartate is protonated.
  2. the R group of glutamate is protonated.
  3. the R group of arginine is protonated.
  4. the R group of lysine is acidic.
  5. the R group of arginine is acidic.

 

Answer: C

Section: 4.1

Level: Hard

Blooms: Understanding

 

 

  1. The flexibility of the polypeptide backbone:

 

  1. allows maximum rotation of the unbranched R groups.
  2. allows resonance between trans and cis configurations.
  3. is limited by the resonance between the alpha carbon and carboxyl oxygen.
  1. is limited by resonance between the carboxyl oxygen and amide nitrogen.
  2. is determined by balance between polar and nonpolar R groups.

 

Answer: D

Section: 4.1

Level: Medium

Blooms: Understanding

 

 

  1. A Ramachandran plot shows the sterically limited rotational domains:

 

  1. between proline and noncylic amino acids.
  2. between polar and nonpolar R groups.
  3. of an R group with respect to the neighboring R groups.
  4. of an R group with respect to the polypeptide backbone.
  5. that two polypeptide chains can occupy.

 

Answer: D

Section: 4.1

Level: Medium

Blooms: Understanding

 

 

  1. At pH 7, a peptide with the sequence G-M-G-V-S-D-P-D-A has a net charge of:

 

  1. -3
  2. -2
  3. -1
  4. +1
  5. +2

 

Answer: B

Section: 4.1

Level: Medium

Blooms: Applying

 

 

  1. At pH 11, a peptide with the sequence G-M-G-V-S-D-P-D-A has the net charge of:

 

  1. -3
  2. -2
  3. -1
  4. +1
  5. +2

 

Answer: A

Section: 4.1

Level: Hard

Blooms: Applying

 

 

  1. The ? helix contains ______________ amino acids residues per turn. One full turn of the ? helix is ______________ long.

 

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